For many Nigerian students, gaining admission into science courses at the university level is highly competitive. Whether you aim to study Medicine, Engineering, Computer Science, Pharmacy, or Nursing, selecting the correct JAMB Direct Entry (DE) subject combination is crucial for success. Using the right subject combination ensures you meet the admission requirements of your chosen course and university, reducing the risk of rejection.

In 2026/2027, universities remain consistent with their subject requirements, but minor changes in policy and eligibility criteria may occur. This comprehensive guide provides everything students need to know about JAMB Direct Entry subject combination for science courses, including eligibility, subject requirements for each course, tips for selection, and common mistakes to avoid.

We will cover:

  • What JAMB Direct Entry is and how it works for science courses

  • Why the correct subject combination matters

  • Detailed subject combinations for all major science courses

  • Eligibility criteria for Direct Entry in Nigeria

  • Step-by-step guide to JAMB DE registration

  • Common mistakes to avoid

  • Comparison table of science courses and required subjects

  • FAQs and expert tips


What is JAMB Direct Entry?

Understanding JAMB Direct Entry (DE)

The Joint Admissions and Matriculation Board (JAMB) Direct Entry (DE) is a pathway for students to gain university admission into 200-level or equivalent courses. This pathway is designed for candidates who have completed one of the following:

  • A-Level programs (WAEC GCE, NECO GCE, IJMB, JUPEB)

  • National Diploma (ND) from recognized polytechnics

  • Other recognized pre-degree programs

Direct Entry bypasses the need to start in 100-level and allows students to leverage previous academic qualifications.

How JAMB Direct Entry Works for Science Courses

Science courses, due to their technical and competitive nature, require candidates to demonstrate mastery in specific subjects. JAMB ensures that DE applicants submit results in relevant subjects to qualify.

For example:

  • Medicine and Surgery: Strong performance in Biology, Chemistry, and Physics is necessary.

  • Engineering: Mathematics, Physics, and Chemistry are usually compulsory.

  • Computer Science: Mathematics and Physics are core requirements.

By following the prescribed DE subject combinations, students can maximize their chances of gaining admission into reputable Nigerian universities.


Why the Correct Subject Combination Matters

Selecting the right JAMB Direct Entry subject combination is critical for several reasons:

  1. Eligibility Verification: Universities will check your DE subject combination before admission. Using incorrect subjects may lead to automatic disqualification.

  2. Competitive Advantage: Science courses are highly competitive. Strong performance in required subjects increases your chances of securing a place.

  3. Smooth Academic Transition: DE candidates start in 200-level; having relevant subjects ensures you can handle advanced coursework without difficulty.

  4. Avoiding Wasted Resources: Registering with the wrong subjects can lead to lost application fees, wasted time, and missed admission opportunities.


JAMB Direct Entry Subject Combination for Popular Science Courses

Here is a detailed breakdown of subject combinations for commonly sought science courses in Nigerian universities:

1. Medicine and Surgery

  • Compulsory Subjects: Biology, Chemistry, Physics

  • Additional Notes:

    • Some universities may require Use of English credit.

    • Strong focus on Biology is crucial for competitive selection.

2. Nursing Science

  • Compulsory Subjects: Biology, Chemistry, Physics

  • Additional Notes:

    • Some schools accept Health Science as an elective in place of Physics.

    • JUPEB, A-Level, or ND results can be used for Direct Entry.

3. Pharmacy

  • Compulsory Subjects: Chemistry, Biology, Physics/Mathematics

  • Additional Notes:

    • Chemistry is critical for pharmacology and lab courses.

    • Universities may prioritize Chemistry grades in admission selection.

4. Engineering (Civil, Mechanical, Electrical, etc.)

  • Compulsory Subjects: Mathematics, Physics, Chemistry

  • Additional Notes:

    • Technical knowledge in Mathematics and Physics is essential.

    • Some universities may allow Technical Drawing or Further Mathematics as electives.

5. Computer Science / Information Technology

  • Compulsory Subjects: Mathematics, Physics, Chemistry

  • Additional Notes:

    • Some schools may accept Computer Studies as an elective.

    • Strong Mathematics foundation is critical for programming and algorithms.

6. Microbiology / Biotechnology / Biological Sciences

  • Compulsory Subjects: Biology, Chemistry, Physics/Mathematics

  • Additional Notes:

    • For specialized programs, Physics may be waived in favor of additional Biology-related subjects.

7. Biochemistry / Chemistry / Industrial Chemistry

  • Compulsory Subjects: Chemistry, Biology/Physics, Mathematics

  • Additional Notes:

    • Chemistry must be a strong focus; universities may check DE grades closely.

8. Physics / Geology / Geophysics

  • Compulsory Subjects: Physics, Mathematics, Chemistry

  • Additional Notes:

    • Strong analytical and numerical skills are emphasized.

    • Some universities require additional subjects like Geography for Geology courses.


Eligibility Criteria for JAMB Direct Entry in Science Courses

To apply for Direct Entry in science courses, candidates must meet the following general eligibility criteria:

  1. Completion of Recognized Pre-Degree Program: A-Level, JUPEB, IJMB, ND, or equivalent.

  2. Minimum Grades: Most universities require at least ‘B’ or credit passes in relevant subjects.

  3. Age Limit: Typically 16–30 years, though exceptions may exist.

  4. Good Conduct and Academic Integrity: Verified by your pre-degree institution.

  5. JAMB DE Registration: Candidates must register with JAMB DE portal and provide valid results.


Step-by-Step Guide to JAMB Direct Entry Registration for Science Courses

  1. Choose Your Course and University: Identify your preferred science course and check the university’s DE requirements.

  2. Obtain Pre-Degree Results: Ensure you have recognized A-Level, JUPEB, or ND results.

  3. Register on JAMB DE Portal: Use JAMB portal for DE registration; provide your pre-degree results.

  4. Submit Correct Subject Combination: Confirm that your subjects match the university’s requirement.

  5. Print DE Registration Slip: Keep a copy for admission verification.

  6. Apply to Universities: Submit your DE application to your chosen universities with supporting documents.

  7. Follow Up: Monitor admission status online and respond to any additional requests (e.g., interviews, screening).


Common Mistakes to Avoid

  • Incorrect Subject Selection: Registering with subjects not recognized by the university.

  • Missing Pre-Degree Results: Failing to submit results in time can delay or nullify admission.

  • Ignoring University-Specific Requirements: Each university may have slight variations; always check the latest DE guide.

  • Neglecting Use of English: Many universities require at least a credit in Use of English.

  • Late Registration: Delays in DE registration may result in missed deadlines.


Summary Table: JAMB Direct Entry Science Courses & Required Subjects

Course Compulsory Subjects Notes Eligible Pre-Degree Programs
Medicine & Surgery Biology, Chemistry, Physics Use of English credit required A-Level, JUPEB, IJMB, ND in related field
Nursing Science Biology, Chemistry, Physics Health Science may replace Physics in some schools A-Level, JUPEB, IJMB, ND
Pharmacy Chemistry, Biology, Physics/Maths Strong Chemistry focus A-Level, JUPEB, IJMB, ND
Engineering Mathematics, Physics, Chemistry Technical Drawing optional A-Level, JUPEB, IJMB, ND
Computer Science Mathematics, Physics, Chemistry Computer Studies optional A-Level, JUPEB, IJMB, ND
Biochemistry Chemistry, Biology/Physics, Mathematics Chemistry is core A-Level, JUPEB, IJMB, ND
Physics Physics, Mathematics, Chemistry Analytical skills emphasized A-Level, JUPEB, IJMB, ND
Geology/Geophysics Physics, Mathematics, Chemistry Geography may be required A-Level, JUPEB, IJMB, ND

Frequently Asked Questions (FAQs)

  1. What is the JAMB Direct Entry requirement for science courses?
    Candidates must have completed recognized pre-degree programs with strong grades in relevant subjects.

  2. Can I use JUPEB for Direct Entry into Medicine?
    Yes. JUPEB is widely accepted for 200-level entry into Medicine and other science courses.

  3. Do all universities accept the same DE subject combination?
    No. While most science courses require similar subjects, slight variations exist. Always check the university’s DE guide.

  4. Can ND graduates apply for science courses via Direct Entry?
    Yes. ND graduates from recognized polytechnics are eligible for Direct Entry.

  5. How long does it take to process DE admission?
    Typically 4–8 weeks, depending on university and verification of results.

  6. Is Physics compulsory for all science courses?
    Not always. Some courses like Nursing or Biochemistry may allow elective substitutions.

  7. Can I change my subject combination after registration?
    Usually not. JAMB allows corrections before final submission, but post-submission changes are limited.

  8. Do I need to write UTME if using DE?
    No. Direct Entry candidates bypass 100-level UTME requirements.

  9. Are DE admissions more competitive than UTME?
    Yes. Limited slots for DE make it highly competitive, especially for Medicine, Pharmacy, and Engineering.

  10. Can I apply to multiple universities with the same DE result?
    Yes. Ensure that your DE subject combination meets the requirements of all selected universities.

  11. Do universities conduct interviews for science courses?
    Some do, particularly Medicine, Nursing, and Pharmacy; others rely solely on DE results.


Conclusion: Secure Your Science Career Through JAMB Direct Entry

Choosing the correct JAMB Direct Entry subject combination is crucial for a successful admission into science courses in Nigeria. It ensures eligibility, strengthens your academic foundation, and positions you competitively for limited slots in top universities.

By carefully selecting your pre-degree subjects, registering correctly on JAMB DE portal, and adhering to university-specific requirements, you can maximize your chances of gaining admission into 200-level for your chosen science course.

Take action now: verify your subject combination, prepare your pre-degree results, and submit your Direct Entry application for the 2026/2027 session. A well-planned DE registration is the first step toward a successful career in science.